| Insert |
DNA: cDNA Insert lengths(kb): 3.349999904632568 Tissue: kidney Gene product: transforming growth factor, alpha(transforming growth factor alpha) [TGFA] Alleles: A1, A2, B1, B2 |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--3.1 (doublet); SalI--6.2; EcoRI/SalI--3.1, 2.6, 0.68; BamHI--4.2, 1.7; PvuI--6.2. Contains 3.3 kb of 3' untranslated sequences and a poly(A) tract. The BamHI polymorphism is in linkage disequilibrium with a RsaI polymorphism detected by phTGF1-10-925, (r=0.55, p=0.03). Enzyme(s) not detecting polymorphism: BclII, BglII, EcoRI, EcoRV, HaeIII, HindIII, HinfI, KpnI, MspI, PstI, PvuII, SacI, XbaI, XhoI. |
| References |
Tricoli JV, et al. The gene for human transforming growth factor alpha is on the short arm of chromosome 2. Cytogenet. Cell Genet. 42: 94-98, 1986. PubMed: 3459638
Murray JC, et al. RFLPs for transforming growth factor alpha (TGFA) gene at 2p13. Nucleic Acids Res. 14: 7136, 1986. PubMed: 2876411
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