| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--2.6, 2.2; PstI--3.4, 1.4; BglII--4.8; PvuII--2.4, 2.3; HindIII--3.2, 1.6; BamHI--4.8. The insert contains the following restriction sites (approximate kb from the 5' end): PstI--0.1, 1.1; BglII--1.1; HindIII--1.6; SstI--1.8. A repeat-free probe from a fragment located immediately 3' to the gene. Does not contain exons. Enzymes(s) not detecting polymorphism: EcoRI, BglII, BamHI, HindIII, Asp700, TaqI, MspI, RsaI, PstI. |
| References |
Bapat B, et al. The human tyrosine kinase gene (FER) detects an RFLP with BglI. Nucleic Acids Res. 19: 4310, 1991. PubMed: 1678513
Morris C, et al. The human tyrosine kinase gene (FER) maps to chromosome 5 and is deleted in myeloid leukemias with a del(5q). Cytogenet. Cell Genet. 53: 196-200, 1990. PubMed: 2209086
John Groffen, personal communication
|
