| Insert |
DNA: genomic Insert lengths(kb): 1.700000047683716 Tissue: placenta St Gene product: immunoglobulin kappa variable region [IGKV] Alleles: Gd, Nd, Gd, Gd, Gd, Gp, Nd, Nd, Np, Np, Np, Gp, Gp, Nd, Gd, Nd, Gd, Nd, Gd, Nd, Gd, Nd, Np, Gp, Np, Gp, Np, Gp, Np, Gp |
| Comments |
Restriction digests of the clone give the following sizes (kb): BamHI--2.7, 1.7; HindIII--2.8, 1.6; PvuI--3.5, 0.9; BglI/PstI--1.8, 1.4, 1.1; BglI--3.3, 1.1. The insert contains an EcoRV site 0.1 kb from one end. Detects sequences from the Op (between O13 and O14) and the Od (between O3 and O4) regions. The BamHI polymorphism can be used only for haplotype N. |
| References |
Pargent W, et al. Polymorphisms and haplotypes in the human immunoglobulin kappa locus. Eur. J. Immunol. 21: 1829-1835, 1991. PubMed: 1678350
Pargent W, et al. The human immunoglobulin kappa locus. Characterization of the duplicated O regions. Eur. J. Immunol. 21: 1821-1827, 1991. PubMed: 1907917
Hans G Zachau, personal communication
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