| 產品名稱 |
B2EE-2.0 |
| 商品貨號 |
B214342 |
| Designations |
B2EE-2.0 |
| Species |
Homo sapiens, human |
| Depositors |
R Baer |
| Vector |
Construct size (kb): 4.699999809265137 |
| Insert |
DNA: genomic Insert lengths(kb): 2.0 Tissue: T-acute lymphocytic leukemia T-lymphocyte Gene product: T-cell acute lymphocytic leukemia 1 (NOTE: redefinition of symbol)(T cell lymphoma 5, helix-loop-helix protein tal-1, 34 kDa) [TAL*] |
| Insert Size (kb) |
2.0 |
| Media |
ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin
|
| Biosafety Level |
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information |
Distributed: freeze-dried |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--2.8, 2.0; HindIII--4.7; BamHI--4.7; PstI--4.7; SalI--4.7. The translocation breakpoint on chromosome 14 in the 2 patients characterized occurred either immediately upstream of Ddelta2-Jdelta1 sequences or within Jdelta1 sequences of the T cell receptor. The insert is derived from sequences adjacent to or involved in translocations in 2 T-ALL patients t(1;14)(p32;q11) and retained on the der(1) chromosome. |
| References |
Chen Q, et al. The tal gene undergoes chromosme translocation in T cell leukemia and potentially encodes a helix-loop-helix protein. EMBO J. 9: 415-424, 1990. PubMed: 2303035
|
