| Comments |
Restriction digests of the clone give the following sizes (kb): PstI--3.8, 0.5; SalI--4.3; PvuII--4.3; BamHI--4.3; HindIII--4.3. The insert includes the entire coding sequence (plus part of signal peptide), 144 bp of the 3' untranslated region, and poly(A) tail. The insert corresponds to mRNA coding for entire plasma form of APOC2. The polymorphic TaqI site is about 2 kb 3' of APOC2 gene; the site is in linkage disequilibrium with BanI site. |
| References |
Jackson CL, et al. Isolation and sequence of a human apolipoprotein CII cDNA clone and its use to isolate and map to human chromosome 19 the gene for apolipoprotein CII. Proc. Natl. Acad. Sci. USA 81: 2945-2949, 1984. PubMed: 6328478
Lusis AJ, et al. Regional mapping of human chromosome 19: organization of genes for plasma lipid transport (APOC1, -C2, and -E and LDLR) and the genes C3, PEPD, and GPI. Proc. Natl. Acad. Sci. USA 83: 3929-3933, 1986. PubMed: 3459164
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