Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Isolation
Stool from 17 yr. old male with paralytic illness, California, 1952
Product Format
frozen
Storage Conditions
-70°C or colder
Comments
Derived from NIAID V-024-001-012. A21 may be a natural recombinant between poliovirus and rhinovirus (Shafren et al J. Virol 71:4736,1997; Hughes et al, J.Gen Virol 70:2943,1989)
Identical to Coe virus. (Schmidt, NJ et al., Proc. Soc. Exp. Biol. Med. 107: 63, 1961>) Complete destruction of cell sheet in HAm cell cultures occurs within 3 days. A21 is associated with human upper respiratory infections.
Effect on Host
Yes, in vitro effects: Cytopathic effects in tissue culture
CPE, cell rounding and sloughing
Recommended Host
human amnion cells
Recommended Host: WISH cells (ATCC? CCL-25?)
human amnion cells in tissue culture
Growth Conditions
Duration: 2-3 days
Name of Depositor
NIH/NIAID
Source
Stool from 17 yr. old male with paralytic illness, California, 1952
Year of Origin
1952
References
Sickles GM, et al. New types of Coxsackie virus, group A. Cytopathogenicity in tissue culture. Proc. Soc. Exp. Biol. Med. 102: 742-743, 1959. PubMed: 14446401
