| Insert |
DNA: genomic Insert lengths(kb): 14.0 Tissue: liver Gene product: DNA Segment, single copy [D8S26] Alleles: A2, B1, B2, B3, B4, A1, A3 |
| Comments |
Restriction digests of the clone give the following sizes (kb): BamHI--26.0, 7.4, 5.8, 3.8; EcoRI--20.0, 11.0, 8.6, 4.2, 1.3; XbaI--20.0, 15.0, 3.8, 3.1; KpnI--20.0, 17.0, 3.0, 1.4; HindIII--22.0, 7.8, 6.6, 5.0, 1.6. The MspI and TaqI polymorphisms have a combined PIC value of 0.67 and a combined heterozygosity of 76%. Enzyme(s) not detecting polymorphism: BglII, PstI, HindIII, EcoRI, RsaI, HincII (panel of 5 individuals). |
| References |
Schumm JW, et al. Identification of more than 500 RFLPs by screening random genomic clones. Am. J. Hum. Genet. 42: 143-159, 1988. PubMed: 2892396
Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638
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