| Insert |
DNA: cDNA Insert lengths(kb): 0.1949999928474426 Gene product: interferon (alpha, beta and omega) receptor 1(interferon, alpha; receptor) [IFNAR] Alleles: A3, A4, A5, A1, A2, A3, A4, A5, A1, A2 |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--3.1; HindIII--uncut; BamHI--3.1; PstI--3.1; EcoRI/SalI--3.0, 0.19. Assignment of the interferon receptor gene to chromosome 21q22.1 was by in situ hybridization. The insert contains upstream non-coding and coding sequences (amino acids 1-39), including nucleotides 1 - 190 of the published sequence. Enzyme(s) not detecting polymorphism: MspI, PstI. |
| References |
Uze G, et al. Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA. Cell 60: 225-234, 1990. PubMed: 2153461
Abdelhak S, et al. HindIII RFLP at the human IFNAR locus. Nucleic Acids Res. 18: 5580, 1990. PubMed: 1699205
Lutfalla G, et al. Assignment of the human interferon alpha receptor gene to chromosome 21q22.1 by in situ hybridization. J. Interferon Res. 10: 515-517, 1990. PubMed: 2148760
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