| Comments |
Restriction digests of the clone give the following sizes (kb): XhoI/XbaI--4.5, 2.95, 0.3 +smaller; EcoRI--3.3, 3.1, 1.6; EcoRV--6.3, 1.7; NdeI--6.4, 1.55; HindIII--4.4, 3.5. Restriction digests of the clone give the following sizes (kb): EcoRI--3.2, 2.9, 1.3; EcoRV--5.7, 1.67; NdeI--5.9, 1.475. This is the homolog of the protein which, when defective in humans, results in choroideremia (CHM). Transcription from the T7 promoter gives the sense strand. |
| References |
Andres DA, et al. cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein. Cell 73: 1091-1099, 1993. PubMed: 8513495
Douglas A Andres, personal communication
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