| Insert |
DNA: genomic Insert lengths(kb): 8.0 Gene product: thyroglobulin [TG] Alleles: D2, D1, B2, A1, A2, A2, B1, B1, B2, A1 |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--8.0, 3.8; HindIII--6.0, 3.4, 1.6, 0.4; PstI--4.3, 3.2 doublet, 0.66; 0.46; AvaI--6.6, 4.8; BamHI--5.2, 3.4, 1.6, 1.3. The insert contains the 5' end of the gene. This probe detects TaqI and HaeIII RFLPs but should not be used alone to detect the HaeIII RFLP because it detects several 0.7 kb HaeIII bands. Use pCHT16/0.7 (ATCC 57436/57437) instead. |
| References |
Baas F, et al. The human thyroglobulin gene, a polymorphic marker marker localized distal to c-myc on chromosome 8 band q24. Hum. Genet. 69: 138-143, 1985. PubMed: 2982724
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