| Components |
NCI-H2126, ATCC CCL-256
NCI-H1299, ATCC CRL-5803
NCI-H1437, ATCC CRL-5872
NCI-H1563, ATCC CRL-5875
NCI-H1573, ATCC CRL-5877
NCI-H1975, ATCC CRL-5908
NCI-H661, ATCC HTB-183 |
| Applications |
Biological understanding of top genetic alterations across tumor types Validation and characterization of potential cancer driver genes Functional profiling and molecular profiling of subtype-specific cancer cell lines Testing small molecules or biologics for cancer drug development |
| Comments |
A panel of 7 lung cancer cell lines with varying degrees of genetic complexity. They have genomic mutations in one or more of the following genes according to the Sanger COSMIC database: CDKN2A, EGFR, KRAS, NRAS, PIK3CA, PIK3R1, SMARCA4, STK11, and TP53. |
