| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--4.8, 3.0; HindIII--3.1, 4.0, 0.52; BamHI--5.2, 2.7; PvuII--3.4, 2.5, 1.0, 0.44, 0.26; XbaI--7.8; PstI--3.0, 1.2, 1.0, 0.90, 0.80, 0.52, 0.28. Restriction digests of the plasmid give the following sizes (kb): EcoRI--5.0, 2.96; HindIII--4.4, 3.4; BamHI--5.3, 2.7. Contains exon 5, a portion of intron 4, and 3' flanking sequences. |
| References |
Poller W, et al. Cloning of the human alpha2-macroglobulin gene and detection of mutations in two functional domains: the bait region and the thiolester site. Hum. Genet. 88: 313-319, 1992. PubMed: 1370808
Faber JP, et al. The molecular basis of alpha 1-antichymotrypsin deficiency in a heterozygote with liver and lung disease. J. Hepatol. 18: 313-321, 1993. PubMed: 8228125
et al., et al. . Am. J. Hum. Genet. 49: 134, 1991.
Wolfgang Poller, personal communication
|
