Amycolatopsis orientalis (Pittenger and Brigham) Lechevalier et al.
商品貨號
B235501
Deposited As
Actinoplanacete sp.
Strain Designations
MA6559
Application
Produces demethomycin
Isolation
Soil
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
freeze-dried
Storage Conditions
Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section
Disclosure
This material is cited in a US or other Patent and may not be used to
infringe the claims. Depending on the wishes of the Depositor, ATCC may be
required to inform the Patent Depositor of the party to which the material was
furnished. This material may not have been produced or characterized by ATCC.
Preceptrol®
no
Type Strain
no
Comments
Desmethylation of immunosuppressants FK-506 and FR900520
Transformation of DuP 753 (= MK 954)
Medium
ATCC® Medium 1877: ISP Medium 1
ATCC® Medium 196: Yeast malt extract agar
Arison BH, et al. Immunosuppressant compound. US Patent 4,981,792 dated Jan 1 1991
Chen TS, et al. Microbial transformation of immunosuppressive compounds. I. Desmethylation of FK506 and immunomycin (FR 900520) by Actinoplanes sp. ATCC 53771. J. Antibiot. 45: 118-123, 1992. PubMed: 1372307
Chen TS, et al. Microbial hydroxylation and glucuronidation of the angiotensin II (AII) receptor antagonist MK 954. J. Antibiot. 46: 131-134, 1993. PubMed: 8436545
