| Comments |
Constructed from DNA from NIH 3T3 cell transformed by rat mammary tumor induced by nitroso-methyl urea. Restriction digests of the clone give the following sizes (kb): BamHI--6.8, 4.5; HindIII--5.6, 3.15, 2.5; EcoRV--5.8, 5.2; EcoRI--11.5. Insert contains NaeI, PvuII (3), SacI (3), HindIII (2), MstI, BstEII (2), HpaI (2), and EcoRV sites. Four exons demonstrated. G to A transition in codon 12 leads to activation of this p21. |
