| 產品名稱 |
Human herpesvirus 1 |
| 商品貨號 |
B237637 |
| Classification |
Herpesviridae, Simplexvirus |
| Agent |
Human herpesvirus 1 |
| Strain |
MP [mutant strain of herpes simplex virus type 1] |
| Common Name |
Herpes simplex virus 1 |
| Applications |
Sexually Transmitted Disease Research |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format |
frozen |
| Storage Conditions |
-70°C or colder |
| Comments |
DNA of strain MP is about 95 X 10(6) daltons in molecular weight--4 million less than wild type. |
| Effect on Host |
CPE (syncytial areas forming large plaques, monolayer sloughing) |
| Recommended Host |
A549 (ATCC® CCL-185™) |
| Growth Conditions |
Temperature: 37°C
Recommendations for Infection: For best results cells should be 24 to 48 hours old and 80%-90% confluent (not 100% confluent).
Incubation: 1-3 days |
| Name of Depositor |
B. Roizman |
| Source |
ATCC® VR-1383™ was derived by passage of ATCC® VR-735™ in presence of Mycoplasma Removal Agent (ICN) to remove contaminating mycoplasma. Human tissue/FL cell culture mutant of type 1 strain selected on basis of its ability to cause cell fusion. |
| References |
Hoggan MD, Roizman B. The isolation and properties of a variant of Herpes simplex producing multinucleated giant cells in monolayer cultures in the presence of antibody. Am. J. Hyg. 70: 208-219, 1959. PubMed: 14402487
Roizman B, et al. Herpes simplex viruses I and II: a biochemical definition. Perspect. Virol. 8: 129-169, 1973.
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