| Comments |
EcoRI digest contains fragments of 20, 11 (doublet), 4.2 and 3.1 kb. EcoRI + HindIII gives fragments of 20, 6.3, 5.7, 3.9, 3.15, 3.0, 1.75, 1.4, 1.1 kb. Restriction digests of the clone give the following sizes (kb): EcoRI--20.0, 11.0 (doublet), 4.0, 3.0; BamHI--20.0, 11.0, 6.0, 5.2, 4.0, 1.5, 0.52; HindIII--21.0, 12.5, 6.1, 3.7, 3.0, 1.7, 1.05; SalI--uncut. Contains the entire coding region of prodynorphin. A 3.0 kb fragment was used as a probe in A0768. It contains the entire coding region. |
| References |
Litt M, et al. Chromosomal localization of the human proenkephalin and prodynorphin genes. Am. J. Hum. Genet. 42: 327-334, 1988. PubMed: 2893547
Horikawa S, et al. Isolation and structural organization of the human preproenkephalin B gene. Nature 306: 611-614, 1983. PubMed: 6316163
James Douglass, personal communication
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